Toward better treatment of clogged arteries
Toward better treatment of clogged arteries
Authors: Guy Lamouche, Sébastien Vergnole, Hamed Azarnoush
Publication date: 2011
Journal: Proceedings of SPIE
Description: Intravascular optical coherence tomography (IVOCT) is a catheter-based technique that provides detailed cross-sectional imaging of the artery wall with a resolution of the order of ten micrometers. The clinical relevance of IVOCT has been demonstrated in many studies for the diagnosis and treatment monitoring of atherosclerosis1 (hardening and/or thickening of arteries by deposited plaques of cholesterol and other lipids, inflammatory cells, and calcium deposits). The technology is mature enough to be distributed commercially. 2 Images may be acquired during a ‘pullback’(backward translation of the imaging probe usually at a predetermined speed), so that pictures are obtained at different positions along the inside of the artery. In OCT, an intravascular pullback also usually includes a rotation of the probe. This minimally invasive technology has evolved tremendously over the last few years to allow fast pullbacks (rotation and translation) over tens of millimeters during a few seconds. IVOCT not only provides a detailed imaging of the atherosclerotic structures over a large segment of an artery, but also allows realistic 3D reconstructions. Our research group investigates further applications of the IVOCT technology. One field of interest is the development of percutaneous (through-the-skin) coronary intervention (PCI) devices. For example, IVOCT can be used to monitor the inflation of an angioplasty balloon in a deployment tester. 3 In balloon angioplasty, a balloon-tipped catheter is inserted into an artery and inflated. The balloon must be well designed to ensure success of the procedure. A deployment tester is used to test the quality of balloons …
Total citations: 1
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